Human embryos from in vitro fertilisation in culture in an
IVF lab usually reach blastocyst stage by day 5 after fertilisation.
Blastocyst is an embryo which has developed to day 5 stage
with different cell components and a fluid cavity.
At blastocyst stage of development, the embryo must reach
before it can implant in the uterus.
Blastocyst embryos
have the best potential for implantation.
Blastocyst culture offers single embryo transfer and
significantly reduce the risk of multiple pregnancy.
Blastocyst culture can help to determine which embryos have
the best chance of being able to implant.
Extended culture allows the embryologist to identify which of
a group of embryos have the best potential for implantation.
If IVF does not work repeatedly with good embryos replaced
on day 2 or 3, blastocyst culture can be tried.
Extended culture allows the embryologist to identify which
of a group of embryos have the best potential for however the chances of having
no embryos for transfer at all are also higher.
Transferring embryos at the blastocyst stage also provides a
better co-ordination between the embryo and the uterus by putting the embryo
back in the uterus at the right time.
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